Amniotic fluid cell
“Aging” refers to the death of the human body, or the aging cells are not replaced or renewed in time; almost every part of the human body has stem cells. “Stem cells” can create new body cells, so they are related to organ function degradation and injury recovery. Closely related.
However, the source of stem cells is closely related to its differentiation ability and medical potential. It is commonly recognized that the younger the stem cells, the better the medical potential.
Many kinds of stem cells
Amniotic fluid cells, a safe version of embryonic stem cells
Fetal stem cells shed into amniotic fluid are so-called “amniotic fluid cells”, and their number is tens of thousands of times of adult stem cells. As long as pregnant women undergo routine amniocentesis, a small amount of amniotic fluid is drawn to obtain the demand. It will not harm or kill the fetus, so there is no moral dispute.
Although embryonic stem cells can differentiate into almost all types of cells in the human body, but because of their excessive differentiation ability, teratoma will form in the place after transplantation, so it cannot be used for stem cell transplantation. However, a paper published in Nature Biotechnology in 2017 showed that amniotic fluid cells can also differentiate into cells of three germ layers, the differentiation ability is similar to embryonic stem cells; but amniotic fluid cells will not form teratomas, and its safety is higher than embryonic stem cells .
Since then, clinical research on amniotic fluid cells has rapidly developed.
Amniotic Fluid Cells ≧ Embryonic Stem Cells
Top of the world
Prove that amniotic fluid cells can differentiate into three germ layer cells.
Studies have shown that amniotic fluid stem cells can differentiate into cells of endoderm, mesoderm, and ectoderm (different from adult mesenchymal stem cells) like differentiated stem cells.
This shows that amniotic fluid stem cells are the cells closest to the recombinant stem cells, and will not harm the fetus when obtained, which is a very good source of stem cells.
The research result was published in Nature Biotechnology, a top journal in the field of biotechnology, and was selected as the cover paper.
Great clinical application potential
Because its differentiation potential and activity are superior to adult stem cells (meat stem cells such as fat, skin, etc.), its medical application potential is great; in Taiwan, amniotic fluid cells have completed preclinical trials of amniotic fluid cells in the treatment of urinary incontinence at the National Yangming University ; Cooperated with Linkou Changgeng Memorial Hospital for clinical trials of rare disease osteogenesis imperfecta, successfully cured 2 glass dolls.